MEKTOVI (binimetinib) tablets

MEKTOVI is a prescription medicine used in combination with a medicine called encorafenib to treat people with a type of skin cancer called melanoma. MEKTOVI (binimetinib) tablets, for oral use Initial U.S. Approval: 2018

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MEKTOVI (binimetinib) tablets

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MEKTOVI (binimetinib) tablets

Binimetinib is used along with encorafenib (Braftovi) to treat certain types of melanoma (a type of skin cancer) that has spread to other parts of the body or cannot be removed by surgery. Binimetinib is in a class of medications called kinase inhibitors.

MEKTOVI is a kinase inhibitor indicated, in combination with encorafenib, for the treatment of patients with unresectable or metastatic melanoma with a BRAF V600E or V600K mutation, as detected by an FDA-approved test. Active ingredient: binimetinib. Inactive ingredients: lactose monohydrate, microcrystalline cellulose, croscarmellose sodium, magnesium stearate (vegetable source), and colloidal silicon dioxide.

Binimetinib, is an anti-cancer medication used to treat various cancers. Binimetinib is a selective inhibitor of MEK, a central kinase in the tumor-promoting MAPK pathway. In June 2018 it was approved by the FDA in combination with encorafenib for the treatment of patients with unresectable or metastatic BRAF V600E or V600K mutation-positive melanoma. In October 2023, it was approved by the FDA for treatment of NSCLC with a BRAF V600E mutation in combination with encorafenib .

Drug (Brand / Generic): ACOVA / Argatroban
Current Indication: treat or prevent blood clots in adults
Approval Date: Aug 1, 2017

Array BioPharma
Tablets: 15 mg
MEKTOVI (binimetinib) is supplied as 15 mg yellow/dark yellow, unscored biconvex oval film-coated tablets debossed with a stylized “A” on one side and “15” on the other side, available in bottles of 180 tablets (NDC 70255-010-02). Store at 20°C to 25°C (68°F to 77°F); excursions permitted between 15°C and 30°C (59°F and 86°F)

For more highlights of prescribing information regarding Indications and usage, dosage and administration, dosage forms and strengths, patient counseling information and medication guide. Click Here

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