COLUMVI (glofitamab-gxbm) injection

Columvi is a cancer medicine used to treat adults with a blood cancer called diffuse large B-cell lymphoma (DLBCL) whose cancer has returned (relapsed) or stopped responding (refractory) after at least two previous treatments.

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COLUMVI (glofitamab-gxbm) injection

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COLUMVI (glofitamab-gxbm) injection

Glofitamab-gxbm is approved to treat: B-cell non-Hodgkin lymphoma (NHL) that has come back or did not get better after at least two other systemic therapies. It is used in adults with the following types of B-cell NHL: Diffuse large B-cell lymphoma (DLBCL).

The Food and Drug Administration (FDA) has granted accelerated approval to Columvi® (glofitamab-gxbm) for the treatment of adult patients with relapsed or refractory (R/R) diffuse large B-cell lymphoma (DLBCL) not otherwise specified or large B-cell lymphoma (LBCL) arising from follicular lymphoma, after 2 or more lines of systemic therapy.

Glofitamab, sold under the brand name Columvi, is a bispecific monoclonal antibody used for the treatment of large B-cell lymphoma.[10] It is a bispecific CD20-directed CD3 T-cell engager.

It was approved for medical use in Canada in July 2023, in the United States in June 2023, and in the European Union in July 2023.

Glofitamab is indicated for the treatment of adults with relapsed or refractory diffuse large B-cell lymphoma. Specifically it is indicated for the treatment of adults with certain types of diffuse large B-cell lymphoma or large B-cell lymphoma who have received at least two prior treatments that did not work or are no longer working.

Drug (Brand / Generic): COLUMVI /glofitamab-gxbm
Current Indication: treat large B-cell lymphoma
Approval Date: 2023

Injection:
 2.5 mg/2.5 mL (1 mg/mL) in a single-dose vial. 
 10 mg/10 mL (1 mg/mL) in a single-dose vial. 

For more highlights of prescribing information regarding Indications and usage, dosage and administration, dosage forms and strengths, patient counseling information and medication guide. Click Here

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