ZALTRAP 25 mg/ml concentrate

ZALTRAP, in combination with fluorouracil, leucovorin, irinotecan-(FOLFIRI), is indicated for the treatment of patients with metastatic colorectal cancer (mCRC) that is resistant to or has progressed following an oxaliplatin-containing regimen.

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ZALTRAP 25 mg/ml concentrate price in India and Overseas
ZALTRAP 25 mg/ml concentrate

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ZALTRAP 25 mg/ml concentrate

Aflibercept, sold under the brand names Eylea and Zaltrap, is a medication used to treat wet macular degeneration and metastatic colorectal cancer.

Zaltrap is a cancer medicine used to treat adults with metastatic colorectal cancer (cancer of the large bowel that has spread to other parts of the body) for whom treatment based on another medicine, oxaliplatin, has not worked or the cancer got worse. Zaltrap is used with FOLFIRI, which is a treatment combining the medicines irinotecan, 5-fluorouracil, and folinic acid. The medicine contains the active substance aflibercept. The European Commission granted a marketing authorisation valid throughout the European Union for Zaltrap on 1 February 2013.

Aflibercept (Eylea) is indicated for the treatment of people with neovascular (wet) age-related macular degeneration, macular edema following retinal vein occlusion, diabetic macular edema, diabetic retinopathy, and retinopathy of prematurity. Aflibercept (Zaltrap), in combination with fluorouracil, leucovorin, irinotecan (FOLFIRI), is indicated for the treatment of people with metastatic colorectal cancer that is resistant to or has progressed following an oxaliplatin-containing regimen. It is used for the treatment of wet macular degeneration and is administered as an intravitreal injection, that is, into the eye. For cancer treatment, it is given intravenously in combination with fluorouracil, leucovorin, and irinotecan (FOLFIRI). In August 2014, aflibercept (Eylea) was approved for the treatment of people with visual impairment due to diabetic macular edema, according to the updated summary of product characteristics. In May 2019, the US FDA expanded the indication for aflibercept to include all stages of diabetic retinopathy. In February 2023, the US FDA approved aflibercept (Eylea) as a treatment for retinopathy of prematurity.

Drug (Brand / Generic): ZALTRAP / Ziv-Aflibercept
Current Indications: Colorectal Neoplasms
Marketed by:: Sanofi Winthrop Industrie
Approval Date: 01/02/2013

Available as (Form & Strength): 100 mg/4 mL (25 mg/mL) and 200 mg/8 mL (25 mg/mL).

For more highlights of prescribing information regarding Indications and usage, dosage and administration, dosage forms and strengths, patient counseling information and medication guide. Click Here

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