XERMELO (telotristat ethyl) tablets

Xermelo is a medicine used to treat adults with severe diarrhoea associated with a condition called carcinoid syndrome. Carcinoid syndrome occurs when certain tumours produce and release too much of a substance called serotonin into the blood.

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XERMELO (telotristat ethyl) tablets

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XERMELO (telotristat ethyl) tablets

Used for the Treatment of carcinoid syndrome diarrhea in combination with somatostatin analog (SSA) therapy in adults inadequately controlled by SSA therapy.

Xermelo is a tryptophan hydroxylase inhibitor indicated for the treatment of carcinoid syndrome diarrhea in combination with somatostatin analog (SSA) therapy in adults inadequately controlled by SSA therapy.

Telotristat ethyl is a prodrug of telotristat, which is an inhibitor of tryptophan hydroxylase. It is formulated as telotristat etiprate — a hippurate salt of telotristat ethyl.

On February 28, 2017, the U.S. Food and Drug Administration (FDA) approved telotristat ethyl in combination with somatostatin analog (SSA) therapy for the treatment of adults with diarrhea associated with carcinoid syndrome that SSA therapy alone has inadequately controlled. Telotristat ethyl was approved for use in the European Union in September 2017.

Drug (Brand / Generic): XERMELO / telotristat ethyl
Current Indication: treat carcinoid syndrome diarrhea
Approval Date: 2017

For more highlights of prescribing information regarding Indications and usage, dosage and administration, dosage forms and strengths, patient counseling information and medication guide. Click Here

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