QARZIBA (Dinutuximab beta) 4.5 mg/mL concentrate for solution for infusion

Qarziba is a cancer medicine used to treat neuroblastoma, a cancer of nerve cells, in patients over 1 year of age. Brand Name: Qarziba 4.5 mg/mL concentrate for solution for infusion. FDA approved Dinutuximab (brand name QARZIBA) is not (yet) registered or available in India but on request Indian patient can buy QARZIBA at the lowest price.

QARZIBA (Dinutuximab beta) injection price in India
Qarziba (Dinutuximab beta) 4.5 mg/mL concentrate for solution for infusion

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Qarziba (Dinutuximab beta) 4.5 mg/mL concentrate for solution for infusion

Dinutuximab is used as post-consolidation therapy for children with high-risk neuroblastoma, in combination with granulocyte-macrophage colony-stimulating factor, interleukin-2, 13-cis-retinoic acid.

Qarziba is indicated for the treatment of high-risk neuroblastoma in patients aged 12 months and above, who have previously received induction chemotherapy and achieved at least a partial response, followed by myeloablative therapy and stem cell transplantation, as well as patients with history of relapsed or refractory neuroblastoma, with or without residual disease. Prior to the treatment of relapsed neuroblastoma, any actively progressing disease should be stabilised by other suitable measures.
In patients with a history of relapsed/refractory disease and in patients who have not achieved a complete response after first line therapy, Qarziba should be combined with interleukin-2 (IL-2).

Dinutuximab beta is a mouse-human chimeric monoclonal IgG1 antibody produced in a mammalian cell line (CHO) by recombinant DNA technology. Dinutuximab beta is used as a second line treatment for children with high-risk neuroblastoma; it was tested and is used with a longer and slower dosing regime, and is given on its own, although it may be combined with IL-2 if a stronger immune response is needed. Dinutuximab beta received marketing approval in Europe in 2017.

Dinutuximab received marketing approval in the US and in the European Union in March 2015;[6][7] the marketing approval was withdrawn in 2017.[7] Dinutuximab beta received marketing approval in Europe in 2017.

Drug (Brand / Generic): QARZIBA / Dinutuximab beta injection
Current Indications: neuroblastoma
Marketed by:: Recordati Netherlands B.V.
Approval Date: 08/05/2017

1 mL of concentrate contains 4.5 mg dinutuximab beta. Each vial contains 20 mg dinutuximab beta in 4.5 mL.

For more highlights of prescribing information regarding Indications and usage, dosage and administration, dosage forms and strengths, patient counseling information and medication guide. Click Here

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