TRIKAFTA (elexacaftor, tezacaftor, and ivacaftor) tablets

TRIKAFTA is a prescription medicine used for the treatment of cystic fibrosis (CF) in patients aged 2 years and older who have at least one copy of the F508del mutation in the cystic fibrosis transmembrane conductance regulator (CFTR) gene or another mutation that is responsive to treatment with TRIKAFTA. brand Name: TRIKAFTA (elexacaftor, tezacaftor, and ivacaftor tablets; ivacaftor tablets), co-packaged for oral use Initial U.S. Approval: 2019. FDA approved elexacaftor, tezacaftor, and ivacaftor (brand name TRIKAFTA) is not (yet) registered or available in India but on request Indian patient can buy TRIKAFTA at the lowest price.

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TRIKAFTA (elexacaftor, tezacaftor, and ivacaftor) tablets Price In India and Overseas
TRIKAFTA (elexacaftor, tezacaftor, and ivacaftor tablets; ivacaftor tablets)

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TRIKAFTA (elexacaftor, tezacaftor, and ivacaftor tablets; ivacaftor tablets)

Elexacaftor/tezacaftor/ivacaftor combination is indicated for the treatment of people aged six years and older who have cystic fibrosis with a F508del mutation or other mutations in the CFTR gene.

TRIKAFTA is a combination of ivacaftor, a CFTR potentiator, tezacaftor, and elexacaftor indicated for the treatment of cystic fibrosis (CF) in patients aged
6 years and older who have at least one F508del mutation in the CFTR gene or a mutation in the CFTR gene that is responsive based on in vitro data.
If the patient’s genotype is unknown, an FDA-cleared CF mutation test should be used to confirm the presence of at least one F508del mutation or a mutation
that is responsive based on in vitro data.

Elexacaftor/tezacaftor/ivacaftor, sold under the brand names Trikafta (US) and Kaftrio (EU), is a fixed-dose combination medication used to treat cystic fibrosis. Elexacaftor/tezacaftor/ivacaftor is composed of a combination of ivacaftor, a chloride channel opener, and elexacaftor and tezacaftor, CFTR modulators.

It is approved for use in the United States for people aged six years and older who have cystic fibrosis with a F508del mutation or other mutations in the CFTR gene. It is also approved for use in Canada, the European Union and Australia.

Drug (Brand / Generic): TRIKAFTA / elexacaftor, tezacaftor, and ivacaftor tablets
Current Indications: cystic fibrosis (CF)
Marketed by:: Vertex Pharmaceutical
Approval Date: 2019

Dosage forms and strengths of TRIKAFTA (elexacaftor, tezacaftor, and ivacaftor tablets; ivacaftor tablets)
Tablets:
• Fixed-dose combination containing elexacaftor 50 mg, tezacaftor 25 mg and ivacaftor 37.5 mg co-packaged with ivacaftor 75 mg.
• Fixed-dose combination containing elexacaftor 100 mg, tezacaftor 50 mg, and ivacaftor 75 mg co-packaged with ivacaftor 150 mg.

For more highlights of prescribing information regarding Indications and usage, dosage and administration, dosage forms and strengths, patient counseling information and medication guide. Click Here

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