SYLVANT (siltuximab) for injection

SYLVANT is indicated for the treatment of adult patients with multicentric Castleman’s disease (MCD) who are human immunodeficiency virus (HIV) negative and human herpesvirus-8 (HHV-8) negative. FDA approved siltuximab (brand name SYLVANT) is not (yet) registered or available in India. The access to the drug is provided as per Name Patient Program respecting the regulatory framework as desired by local authorities.

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SYLVANT (siltuximab) for injection

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SYLVANT (siltuximab) for injection

Siltuximab, is used for the treatment of people with multicentric Castleman's disease.

SYLVANT is indicated for the treatment of adult patients with multicentric Castleman’s disease
(MCD) who are human immunodeficiency virus (HIV) negative and human herpesvirus-8 (HHV-8)
negative.

Siltuximab, sold under the brand name Sylvant, is used for the treatment of people with multicentric Castleman’s disease. It is a chimeric (made from human and mouse proteins) monoclonal antibody that binds to interleukin-6. It is an interleukin-6 (IL-6) antagonist.

Drug (Brand / Generic): SYLVANT (siltuximab) for Injection, for Intravenous infusion
Current Indication: multicentric Castleman’s disease
(MCD)
Approval Date: 2023

  • SYLVANT 100 mg powder for concentrate for solution for infusion
  • SYLVANT 400 mg powder for concentrate for solution for infusion

For more highlights of prescribing information regarding Indications and usage, dosage and administration, dosage forms and strengths, patient counseling information and medication guide. Click Here

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