TALVEY (talquetamab-tgvs) injection

Talvey (talquetamab-tgvs) is a prescription drug that’s used to treat certain types of multiple myeloma. Brand Name: TALVEY (talquetamab-tgvs) injection, for subcutaneous use Initial U.S. Approval: 2023 

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TALVEY (talquetamab-tgvs) injection

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TALVEY (talquetamab-tgvs) injection

Talquetamab-tgvs is used to treat multiple myeloma (a type of cancer of the bone marrow) that has returned or that did not respond to at least 4 other treatments. Talquetamab-tgvs is in a class of medications called bispecific T-cell engager antibodies. It works by killing cancer cells.

TALVEY is a bispecific GPRC5D-directed CD3 T-cell engager indicated for the treatment of adult patients with relapsed or refractory multiple myeloma who have received at least four prior lines of therapy, including a proteasome inhibitor, an immunomodulatory agent and an anti-CD38 monoclonal antibody.

Talquetamab, sold under the brand name Talvey, is a humanized monoclonal antibody used for the treatment of multiple myeloma. It is a bispecific GPRC5D-directed CD3 T-cell engager. Talquetamab is a bispecific antibody against two targets: human CD3, a T-cell surface antigen, and human G-protein coupled receptor family C group 5 member D (GPRC5D), a tumor-associated antigen with potential antineoplastic activity. Talquetamab binds both targets, drawing the T cells close to the tumor cells, causing a cytotoxic T-lymphocyte response.

Talquetamab was approved for medical use in both the United States and the European Union in August 2023. The US Food and Drug Administration (FDA) considers it to be a first-in-class medication.

Drug (Brand / Generic): TALVEY /talquetamab-tgvs
Current Indication: multiple myeloma
Approval Date: 2023

Injection
• 3 mg/1.5 mL (2 mg/mL) in a single-dose vial 
• 40 mg/mL in a single-dose vial 

For more highlights of prescribing information regarding Indications and usage, dosage and administration, dosage forms and strengths, patient counseling information and medication guide. Click Here

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